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In 2009, Governor Ted Strickland designated Dayton as Ohio's aerospace innovation hub, the first such technology hub in the state.
GE Aviation, headquartered in Evendale, is a major manufacturer of aircraft engines globally.
Notable defense contractors include Goodyear Tire and Rubber Company in Akron, Lockheed Martin in Akron, which won a contract to develop a space-ship in 2003 and produces the vertical launch ASROC missile, Columbus-based Zyvex Performance Materials develops the Piranha Unmanned Surface Vessel.
Gravitational Energy Corporation, located in Cuyahoga Falls, proliferates Gravity Assisted Power (GAP) machines in cooperation with Dri Powder, LLC to the military.
In 2013, Ohio was ranked in the top ten states for best business climate by Site Selection magazine, based on a business-activity database. exports in 2009, with top destinations being Canada at .2 billion, followed by Mexico, China, United Kingdom, Greece, Brazil, Japan, Germany, France, and Australia.
The state was edged out by Texas and Nebraska for the 2013 Governor's Cup award from the magazine, based on business growth and economic development. As of 2010, Ohio was #6 in the country for Fortune 500 companies with 23.
Dayton is designated as the state's aerospace hub due to its high concentration of aerospace and aviation technology.In 2010, EPISCENTER, a new R&D center for the corporation to be located in Dayton, was announced by the Third Frontier program.Boeing's Central Ohio Aerospace and Technology Center in Heath is a venture amongst five of the top 10 U. defense contractors, including Atlantic Inertial Systems, Honeywell, Kearfott, Northrop-Grumman, L3 Communications, and Raytheon, which is also the headquarters of the Air Force Metrology and Calibration Program Office.The overall economic impact of the bioscience industry in Ohio, including healthcare, amounted to 8.2 billion in 2007, representing 15.7% of Ohio's economic output.Biotech research and development employs directly 12,415 residents, while agricultural bioscience contributed the largest economic impact, at .7 billion.
Other Ohio cities listed include Cincinnati at #6 and Cleveland at #16. News and World Report ranked the clinic as the fourth best hospital in the country, and the #1 heart center in the country for the 15th year in a row.